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Acetylation at K108 of the NS1 protein is important for the replication and virulence of influenza virus

24 Feb 2020

Abstract excerpt

Non-structural protein 1 (NS1) of influenza virus is a multifunctional protein that plays an important role in virus replication and virulence. In this study, an acetylation modification was identified at the K108 residue of the NS1 protein of H1N1 influenza virus. To further explore the function of the K108 acetylation modification of the NS1 protein, a deacetylation-mimic mutation (K108R) and a constant...

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PMID: 32093780
DOI: 10.1186/s13567-020-00747-3

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