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Article

Different Subtypes of Influenza Viruses Target Different Human Proteins and Pathways Leading to Different Pathogenic Phenotypes.

BioMed research international - 1 Jan 2019

Wang Yujie, Song Ting, Li Kaiwu, Jin Yuan, Yue Junjie, Ren Hongguang, Liang Long

Abstract excerpt

Different subtypes of influenza A viruses (IAVs) cause different pathogenic phenotypes after infecting human bodies. Analysis of the interactions between viral proteins and the host proteins may provide insights into the pathogenic mechanisms of the virus. In this paper, we found that the same proteins (nucleoprotein and neuraminidase) of H1N1 and H5N1 have different impacts on the NF-κB activation. By further...

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Source

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Identifiers

PMID: 31772934
DOI: 10.1155/2019/4794910
PMCID: PMC6854240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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