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Novel Lentivirus-Based Method for Rapid Selection of Inhibitory Nanobody against PRRSV

19 Feb 2020

Abstract excerpt

The emergence and re-emergence of porcine reproductive and respiratory syndrome virus (PRRSV) has resulted in huge economic losses for the swine industry. Current vaccines are of limited efficacy against endemic circulating PRRSV variants. New strategies against PRRSV infection are in urgent need. Here, a nanobody library in Marc-145 cells is constructed for antiviral nanobodies. Nanobody encoding sequences from...

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PMID: 32092857
DOI: 10.3390/v12020229

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