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Article

Meiotic gatekeeper STRA8 regulates cell cycle by interacting with SETD8 during spermatogenesis

24 Feb 2020

Abstract excerpt

STRA8 (Stimulated By Retinoic Acid Gene 8) is a retinoic acid (RA) induced gene that plays vital roles in spermatogonial proliferation, differentiation and meiosis. The SETD8 and STRA8 protein interaction was discovered using the yeast two-hybrid technique using a mouse spermatogonial stem cell (SSC) cDNA library. The interaction of these two proteins was confirmed using co-immunoprecipitation and identification...

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PMID: 32090428
DOI: 10.1111/jcmm.15080

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