Article
Lactonase Activity, Status, and Genetic Variations of Paraoxonase 1 in Women with Gestational Diabetes Mellitus.
Journal of diabetes research - 1 Jan 2020
Zhou Mi, Liu Xing-Hui, Liu Qing-Qing, Chen Meng, Bai Huai, Guan Lin-Bo, Fan Ping
Abstract excerpt
BACKGROUND: Paraoxonase 1 (PON1) is a calcium-dependent multifunctional enzyme that binds to high-density lipoproteins. The physiological function of PON1 is related to its lactonase activity. However, this activity has not been analyzed in women with gestational diabetes mellitus (GDM). The present study investigated the lactonase activities and status of PON1 and their association with PON1 genetic variants and...
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