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Article

Foetal macrosomia and erythrocyte acid phosphatase (ACP1) polymorphism in diabetic and normal pregnancy.

Early human development - 1 Jan 2000

Gloria-Bottini F, Gerlini G, Lucarini N, Borgiani P, Gori M C, Amante A, Lucarelli P, Bottini E

Abstract excerpt

Both in diabetic and in normal pregnancy the proportion of macrosomic fetuses is much lower among newborns carrying Pc allele of erythrocyte acid phosphatase (ACP1) than among other ACP1 genotypes. In diabetic pregnancy the well known increased incidence of fetal macrosomia has been observed only among fetuses which do not carry this allele. ACP1 probably functions as a flavin-mononucleotide phosphatase. Since Pc...

Topics

Acid Phosphatase
Adult
Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Erythrocytes
Female
Fetal Macrosomia
Genotype
Humans
Infant, Newborn
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Pregnancy

Pregnancy in Diabetics

Source

Identifiers

PMID: 3208681

Genes

ACP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3208681-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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