Article
A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism.
Experientia - 15 Jan 1990
Lucarini N, Finocchi G, Gloria-Bottini F, Macioce M, Borgiani P, Amante A, Bottini E
Abstract excerpt
Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.
Topics
- Acid Phosphatase
- Adolescent
- Child
- Child, Preschool
- Erythrocytes
- Female
- Humans
- Male
- Obesity
- Phenotype
- Polymorphism, Genetic
