Article
Idylla EGFR assay on extracted DNA: advantages, limits and place in molecular screening according to the latest guidelines for non-small-cell lung cancer (NSCLC) patients.
Journal of clinical pathology - 1 Oct 2023
Khalifa Emmanuel, Chapusot Caroline, Tournier Benjamin, Sentis Julie, Marion Estelle, Remond Alicia, Aubry Manon, Pioche Célia, Bergeron Anthony, Primois Charlotte, Blanchard Larry, Millière Alice, Boucheix Marlène, Léger Yannick, Bairrao Marine, Brouste Véronique, Martin Laurent, Soubeyran Isabelle
Abstract excerpt
AIMS: Idylla epidermal growth factor receptor (EGFR) is a fast and fully automated mutation assay that is easy to implement. However, under the Biocartis-recommended technical conditions, tissue sections are directly introduced into the cartridge, at the risk of exhausting the tumour sample. In this study, we evaluate the performance of Idylla EGFR on extracted DNA and discuss its place within the global...
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