Mesenchymal Stem/Stromal Cells from the Placentae of Growth Restricted Pregnancies Are Poor Stimulators of Angiogenesis.

doi:10.1007/s12015-020-09959-8

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Mesenchymal Stem/Stromal Cells from the Placentae of Growth Restricted Pregnancies Are Poor Stimulators of Angiogenesis.

Stem cell reviews and reports - 1 Jun 2020

Umapathy Anandita, McCall Alexandra, Sun Cherry, Boss Anna L, Gamage Teena K J B, Brooks Anna E S, Chamley Lawrence Larry W, James Joanna L

Abstract excerpt

The extensively branched vascular network within the placenta is vital for materno-fetal exchange, and inadequate development of this network is implicated in the pregnancy disorder fetal growth restriction (FGR), where babies are born pathologically small. Placental mesenchymal stem/stromal cells (pMSCs) and placental macrophages both reside in close proximity to blood vessels within the placenta, where they are...

Topics

Cell Proliferation
Culture Media, Conditioned
Cytokines
Female
Fetal Growth Retardation
Fluorescent Dyes
Human Umbilical Vein Endothelial Cells
Humans
Macrophages
Mesenchymal Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neovascularization, Physiologic

Phenotype

Placenta

Pregnancy

RNA, Messenger

U937 Cells

Source

Open in PubMed

Identifiers

PMID: 32080795
DOI: 10.1007/s12015-020-09959-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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