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Article

Regulation of vascular growth and function in the human placenta

26 May 2009

Abstract excerpt

During the course of 9 months, the human placenta develops into a highly vascular organ. Vasculogenesis starts during the third week post-conception. Hemangioblastic cell cords differentiate in situ from mesenchymal cells in the villous cores, most probably under the influence of vascular endothelial growth factor (VEGFA) secreted by the overlying trophoblast. The cords elongate through proliferation and cell...

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PMID: 19470597
DOI: 10.1530/rep-09-0092

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