Article
c-di-GMP-related phenotypes are modulated by the interaction between a diguanylate cyclase and a polar hub protein.
Scientific reports - 20 Feb 2020
Nicastro Gianlucca G, Kaihami Gilberto H, Pulschen André A, Hernandez-Montelongo Jacobo, Boechat Ana Laura, de Oliveira Pereira Thays, Rosa Caio Gomes Tavares, Stefanello Eliezer, Colepicolo Pio, Bordi Christophe, Baldini Regina L
Abstract excerpt
c-di-GMP is a major player in the switch between biofilm and motile lifestyles. Several bacteria exhibit a large number of c-di-GMP metabolizing proteins, thus a fine-tuning of this nucleotide levels may occur. It is hypothesized that some c-di-GMP metabolizing proteins would provide the global c-di-GMP levels inside the cell whereas others would maintain a localized pool, with the resulting c-di-GMP acting at...
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