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Article

Role of Heparin-Binding Epidermal Growth Factor-Like Growth Factor in Oxidative Stress-Associated Metabolic Diseases.

Metabolic syndrome and related disorders - 1 May 2020

Kim Seonwook, Subramanian Venkateswaran, Abdel-Latif Ahmed, Lee Sangderk

Abstract excerpt

Heparin-binding EGF-like growth factor (HB-EGF) is an EGF family member that interacts with epidermal growth factor receptor (EGFR) and ERBB4. Since HB-EGF was first identified as a novel growth factor secreted from a human macrophage cell line, numerous pathological and physiological functions related to cell proliferation, migration, and inflammation have been reported. Notably, the expression of HB-EGF is...

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Identifiers

PMID: 32077785
DOI: 10.1089/met.2019.0120
PMCID: PMC7196370

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