Article
Population Structure Analyses Provide Insight into the Source Populations Underlying Rural Isolated Communities in Illinois.
Human biology - 17 Feb 2019
Owings Amanda C, Fernandes Samuel Bonfim, Olatoye Marcus O, Fogleman Amanda J, Zahnd Whitney E, Jenkins Wiley D, Malhi Ripan S, Lipka Alexander E
Abstract excerpt
We have previously hypothesized that relatively small and isolated rural communities may experience founder effects, defined as the genetic ramifications of small population sizes at the time of a community's establishment. To explore this, we used an Illumina Infinium Omni2.5Exome-8 chip to collect data from 157 individuals from four Illinois communities, three rural and one urban. Genetic diversity estimates of...
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