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Article

Yeast filamentation signaling is connected to a specific substrate translocation mechanism of the Mep2 transceptor.

PLoS genetics - 1 Feb 2020

Brito Ana Sofia, Neuhäuser Benjamin, Wintjens René, Marini Anna Maria, Boeckstaens Mélanie

Abstract excerpt

The dimorphic transition from the yeast to the filamentous form of growth allows cells to explore their environment for more suitable niches and is often crucial for the virulence of pathogenic fungi. In contrast to their Mep1/3 paralogues, fungal Mep2-type ammonium transport proteins of the conserved Mep-Amt-Rh family have been assigned an additional receptor role required to trigger the filamentation signal in...

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Identifiers

PMID: 32069286
DOI: 10.1371/journal.pgen.1008634
PMCID: PMC7048316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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