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Article

KMT2D and TP53 mutation status improve the prognostic value of the International Prognostic Index (IPI) stratification in ENKTL patients.

Neoplasma - 1 May 2020

Gao Y, Li Y, Ma G, Zhao G, Liu H

Abstract excerpt

Extranodal NK/T-cell lymphoma nasal type (ENKTL) is a subtype of T cell lymphoma with poor prognosis. In this study, we designed a new prognostic model specifically for ENKTL to improve the risk stratification. In 29 ENKTL patients, we screened mutations in 9 ENKTL-associated genes using next-generation sequencing (NGS). We have found that mutated KMT2D was associated with the inferior overall survival (OS) and...

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Identifiers

PMID: 32064880
DOI: 10.4149/neo_2020_190307N194

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