Article
Analysis of mutation profiles in extranodal NK/T-cell lymphoma: clinical and prognostic correlations.
Annals of hematology - 1 Aug 2024
Chang Yu-Cheng, Tsai Hui-Jen, Huang To-Yu, Su Nai-Wen, Su Ying-Wen, Chang Yi-Fang, Chen Caleb Gon-Shen, Lin Johnson, Chang Ming-Chih, Chen Shu-Jen, Chen Hua-Chien, Lim Ken-Hong, Chang Kung-Chao, Kuo Sung-Hsin
Abstract excerpt
The molecular pathogenesis of extranodal NK/T-cell lymphoma (NKTCL) remains obscured despite the next-generation sequencing (NGS) studies explored on ever larger cohorts in the last decade. We addressed the highly variable mutation frequencies reported among previous studies with comprehensive amplicon coverage and enhanced sequencing depth to achieve higher genomic resolution for novel genetic discovery and...
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