Article
The Phenotype and Functional Activity of Mesenchymal Stromal Cells in Pediatric Patients with Non-Malignant Hematological Diseases.
Cells - 12 Feb 2020
Kuci Zyrafete, Jordan Christiane, Wehner Sibylle, Sörensen Jan, Jarisch Andrea, Salzmann-Manrique Emilia, Pfeffermann Lisa-Marie, Klingebiel Thomas, Bader Peter, Kuҫi Selim
Abstract excerpt
As the biology of mesenchymal stromal cells (MSCs) in patients with non-malignant hematological diseases (NMHD) is poorly understood, in the current study we performed a basic characterization of the phenotype and functional activity of NMHD-MSCs. Bone marrow (BM) of patients with thalassemia major (TM) possessed a significantly higher number of nucleated cells (BM-MNCs)/mL BM than healthy donors (P < 0.0001),...
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