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Article

Dimethylaminophenyl Hydrazides as Inhibitors of the Lipid Transport Protein LprG in Mycobacteria.

ACS infectious diseases - 10 Apr 2020

Bai Lu, Parkin Lia A, Zhang Hong, Shum Rebecca, Previti Mary L, Seeliger Jessica C

Abstract excerpt

Assembly of the bacterial cell wall requires not only the biosynthesis of cell wall components but also the transport of these metabolites to the cell exterior for assembly into polymers and membranes required for bacterial viability and virulence. LprG is a cell wall protein that is required for the virulence of Mycobacterium tuberculosis and is associated with lipid transport to the outer lipid layer or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32053347
DOI: 10.1021/acsinfecdis.9b00497
PMCID: PMC7436943

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