Article
miR‐146b‐5p Plays a Critical Role in the Regulation of Autophagy in ∆per Brucella melitensis‐Infected RAW264.7 Cells
1 Jan 2020
Abstract excerpt
Brucella‐caused brucellosis is one of the most widespread worldwide zoonoses. Lipopolysaccharide (LPS) of Brucella, which functions as pathogen‐associated molecular patterns (PAMPs), is an important virulence factor that elicits protective antibodies. Per of B. melitensis is involved in the biosynthesis of the O‐side chain of LPS. Autophagy is a crucial element of the innate immune response against intracellular...
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