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Article

Immunomodulatory Strategies in Herpes Simplex Virus Encephalitis.

Clinical microbiology reviews - 18 Mar 2020

Piret Jocelyne, Boivin Guy

Abstract excerpt

Herpes simplex virus 1 (HSV-1) can be responsible for life-threatening HSV encephalitis (HSE). The mortality rate of patients with HSE who do not receive antiviral treatment is 70%, with most survivors suffering from permanent neurological sequelae. The use of intravenous acyclovir together with improved diagnostic technologies such as PCR and magnetic resonance imaging has resulted in a reduction in the...

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Identifiers

PMID: 32051176
DOI: 10.1128/CMR.00105-19
PMCID: PMC7018500

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