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Genetic variants in m6A modification genes are associated with esophageal squamous-cell carcinoma in the Chinese population.

Carcinogenesis - 10 Jul 2020

Yang Nan, Ying Pingting, Tian Jianbo, Wang Xiaoyang, Mei Shufang, Zou Danyi, Peng Xiating, Gong Yajie, Yang Yang, Zhu Ying, Ke Juntao, Zhong Rong, Chang Jiang, Miao Xiaoping

Abstract excerpt

N 6-methyladenosine (m6A) is an abundant modification in RNAs that affects RNA metabolism, and it is reported to be closely related to cancer occurrence and metastasis. In this study, we focused on evaluating the associations between genetic variants in m6A modification genes and the risk of esophageal squamous-cell carcinoma (ESCC). By integrating data of our previous genome-wide association studies and the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32047883
DOI: 10.1093/carcin/bgaa012

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