Tumour infiltrating lymphocyte status is superior to histological grade, DNA mismatch repair and BRAF mutation for prognosis of colorectal adenocarcinomas with mucinous differentiation.

doi:10.1038/s41379-020-0496-1

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Article

Tumour infiltrating lymphocyte status is superior to histological grade, DNA mismatch repair and BRAF mutation for prognosis of colorectal adenocarcinomas with mucinous differentiation.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2020

Williams David S, Mouradov Dmitri, Newman Marsali R, Amini Elham, Nickless David K, Fang Catherine G, Palmieri Michelle, Sakthianandeswaren Anuratha, Li Shan, Ward Robyn L, Hawkins Nicholas J, Skinner Iain, Jones Ian, Gibbs Peter, Sieber Oliver M

Abstract excerpt

Mucinous colorectal adenocarcinoma (CRC) is conventionally defined by extracellular mucin comprising >50% of the tumour area, while tumours with ≤50% mucin are designated as having a mucinous component. However, these definitions are largely arbitrary and comparisons of clinico-molecular features and outcomes by proportion of mucinous component are limited. A cohort of 1643 patients with stage II/III cancer was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32047231
DOI: 10.1038/s41379-020-0496-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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