Article
Quantitatively relating brain endothelial cell-cell junction phenotype to global and local barrier properties under varied culture conditions via the Junction Analyzer Program.
Fluids and barriers of the CNS - 11 Feb 2020
Gray Kelsey M, Jung Jae W, Inglut Collin T, Huang Huang-Chiao, Stroka Kimberly M
Abstract excerpt
BACKGROUND: The endothelial cell-cell junctions of the blood-brain barrier (BBB) play a pivotal role in the barrier's function. Altered cell-cell junctions can lead to barrier dysfunction and have been implicated in several diseases. Despite this, the driving forces regulating junctional protein presentation remain relatively understudied, largely due to the lack of efficient techniques to quantify their...
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