Article
A phase I/II study of weekly nab-paclitaxel plus cisplatin in chemotherapy-naïve patients with advanced non-small-cell lung cancer.
BMC cancer - 11 Feb 2020
Hattori Yoshihiro, Kono Yuko, Itoh Shoichi, Inoue Takako, Urata Yoshiko, Kawa Yoshitaka, Tohnai Rie, Kumagai Toru, Nishino Kazumi, Uozumi Ryuji, Morita Satoshi, Negoro Shunichi, Imamura Fumio, Satouchi Miyako
Abstract excerpt
BACKGROUND: The aim of this study was to evaluate the efficacy and safety of nab-paclitaxel plus cisplatin in chemotherapy-naïve patients with advanced non-small-cell lung cancer (NSCLC). METHODS: Chemotherapy-naïve patients with advanced NSCLC were eligible. In the phase I dose-escalation cohort (3 + 3 design), patients received nab-paclitaxel (80 or 100 mg/m2 given intravenously on days 1, 8 and 15) plus...
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