Article
The Efficacy and Safety of Icotinib in Patients with Advanced Non-Small Cell Lung Cancer Previously Treated with Chemotherapy: A Single-Arm, Multi-Center, Prospective Study.
PloS one - 1 Jan 2015
Hu Xingsheng, Zhang Li, Shi Yuankai, Zhou Caicun, Liu Xiaoqing, Wang Dong, Song Yong, Li Qiang, Feng Jifeng, Qin Shukui, Xv Nong, Zhou Jianying, Zhang Li, Hu Chunhong, Zhang Shucai, Luo Rongcheng, Wang Jie, Tan Fenlai, Wang Yinxiang, Ding Lieming, Sun Yan
Abstract excerpt
BACKGROUND: Icotinib is a small molecule targeting epidermal growth factor receptor tyrosine kinase, which shows non-inferior efficacy and better safety comparing to gefitinib in previous phase III trial. The present study was designed to further evaluate the efficacy and safety of icotinib in patients with advanced non-small-cell lung cancer (NSCLC) previously treated with platinum-based chemotherapy. METHODS:...
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