Article
Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan.
Scientific reports - 10 Feb 2020
Lone Nasira M, Riaz Saba, Eusaph Amna Z, Mein Charles A, Wozniak Eva L, Xenakis Theodoros, Wu Zhenqiang, Younis Sidra, Jolliffe David A, Junaid Kashaf, Martineau Adrian R
Abstract excerpt
Both vitamin D deficiency and single nucleotide polymorphisms (SNPs) in the gene encoding the vitamin D receptor (VDR) have been widely reported to associate with susceptibility to polycystic ovarian syndrome (PCOS). A case-control study was conducted to study the influence of vitamin D status and genotpye for 24 SNPs in four genes in the vitamin D pathway (VDR, DBP, CYP27B1, CYP24A1) on PCOS. Statistical...
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