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Target prediction and validation of microRNAs expressed from FSHR and aromatase genes in human ovarian granulosa cells

10 Feb 2020

Abstract excerpt

MicroRNAs (miRNAs) are known post-transcriptional regulators of various biological processes including ovarian follicle development. We have previously identified miRNAs from human pre-ovulatory ovarian granulosa cells that are expressed from the intronic regions of two key genes in normal follicular development: FSH receptor (FSHR) and CYP19A1, the latter encoding the aromatase enzyme. The present study aims to...

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PMID: 32042028
DOI: 10.1038/s41598-020-59186-x

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