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Article

Identification of MicroRNAs controlling human ovarian cell steroidogenesis via a genome‐scale screen

4 Feb 2009

Abstract excerpt

The aim of our studies was to identify miRNAs affecting the release of the major ovarian steroid hormones progestagen, androgen and estrogen by human ovarian cells. The effect of transfection of cultured primary ovarian granulosa cells with 80 different gene constructs encoding human pre-miRNAs on release of progesterone, testosterone and estradiol was evaluated by enzyme immunoassay. In addition, effect of two...

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PMID: 19194990
DOI: 10.1002/jcp.21689

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