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Article

The role of spatial structure in the evolution of viral innate immunity evasion: A diffusion-reaction cellular automaton model.

PLoS computational biology - 1 Feb 2020

Segredo-Otero Ernesto, Sanjuán Rafael

Abstract excerpt

Most viruses have evolved strategies for preventing interferon (IFN) secretion and evading innate immunity. Recent work has shown that viral shutdown of IFN secretion can be viewed as a social trait, since the ability of a given virus to evade IFN-mediated immunity depends on the phenotype of neighbor viruses. Following this idea, we investigate the role of spatial structure in the evolution of innate immunity...

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Identifiers

PMID: 32040504
DOI: 10.1371/journal.pcbi.1007656
PMCID: PMC7034925

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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