PNPLA3 polymorphism influences the association between high-normal TSH level and NASH in euthyroid adults with biopsy-proven NAFLD.

doi:10.1016/j.diabet.2020.02.001

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Article

PNPLA3 polymorphism influences the association between high-normal TSH level and NASH in euthyroid adults with biopsy-proven NAFLD.

Diabetes & metabolism - 1 Nov 2020

Hu D-S, Zhu S-H, Liu W-Y, Pan X-Y, Zhu P-W, Li Y-Y, Zheng K I, Ma H-L, You J, Targher G, Byrne C D, Chen Y-P, Zheng M-H

Abstract excerpt

AIM: We aimed to evaluate the association between serum thyroid stimulating hormone (TSH) levels, within the reference range, and the histological severity of nonalcoholic fatty liver disease (NAFLD), and whether this association was modulated by the patatin-like phospholipase domain-containing 3 (PNPLA3) rs738409 polymorphism. MATERIALS AND METHODS: We enrolled 327 euthyroid individuals with biopsy-proven NAFLD,...

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PMID: 32035968
DOI: 10.1016/j.diabet.2020.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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