Article
Gene expression profiling and association studies implicate the neuregulin signaling pathway in Behçet's disease susceptibility.
Journal of molecular medicine (Berlin, Germany) - 1 Aug 2013
Xavier Joana M, Krug Tiago, Davatchi Fereydoun, Shahram Farhad, Fonseca Benedita V, Jesus Gorete, Barcelos Filipe, Vedes Joana, Salgado Manuel, Abdollahi Bahar Sadeghi, Nadji Abdolhadi, Moraes-Fontes Maria Francisca, Shafiee Niloofar Mojarad, Ghaderibarmi Fahmida, Vaz Patto José, Crespo Jorge, Oliveira Sofia A
Abstract excerpt
Behçet's disease (BD) is a complex disease with genetic and environmental risk factors implicated in its etiology; however, its pathophysiology is poorly understood. To decipher BD's genetic underpinnings, we combined gene expression profiling with pathway analysis and association studies. We com...
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