Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multicentric breast cancer: clonality and prognostic studies.

Breast cancer research and treatment - 1 Oct 2011

Eeles R, Knee G, Jhavar S, Mangion J, Ebbs S, Gui G, Thomas S, Coppen M, A'hern R, Gray S, Cooper C, Bartek J, Yarnold J

Abstract excerpt

Clonality of multicentric breast cancer has traditionally been difficult to assess. We aimed to assess this using analysis of TP53 status (expression and mutation status). These results were then incorporated into an analysis of prognostic factors in multicentric tumours in a 10-year follow up study. Clonal status of multicentric breast cancer foci (n = 88 foci) was determined by immunohistochemical and molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Follow-Up Studies

Share to Gene Expression Regulation, Neoplastic

Share to Polymorphism, Single-Stranded Conformational

Share to Prognosis

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 21080063
DOI: 10.1007/s10549-010-1230-3

Genes

NHS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multicentric breast cancer: clonality and prognostic studies.PMID 21080063Read ↗

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers.Semantic proximity Read ↗

Multicentric breast cancer with heterogeneous histopathology: a multidisciplinary review.Semantic proximity Read ↗

Multifocal breast cancers are more prevalent in<i>BRCA2</i>versus<i>BRCA1</i>mutation carriersSemantic proximity Read ↗

Discrimination between multicentric and multifocal carcinomas of the breast through clonal analysisSemantic proximity Read ↗

Impact of multifocal or multicentric disease on local recurrence and survival in breast cancer patients with or without BRCA1/2 variants.Semantic proximity Read ↗

p53 overexpression and mutation in metaplastic carcinoma of the breast: genetic evidence for a monoclonal origin of both the carcinomatous and the heterogeneous sarcomatous components.Semantic proximity Read ↗

The hormone receptor, human epidermal growth factor receptor 2, and molecular subtype status of individual tumor foci in multifocal/multicentric invasive ductal carcinoma of breast.Semantic proximity Read ↗

Molecular phenotype of the foci in multifocal invasive breast carcinomas: intertumoral heterogeneity is related to shorter survival and may influence the choice of therapy.Semantic proximity Read ↗

Determination of the molecular relationship between multiple tumour nodules in hepatocellular carcinoma differentiates multicentric origin from intrahepatic metastasisSemantic proximity Read ↗

Molecular study of clonality in multifocal and bilateral breast tumors.Semantic proximity Read ↗

[Intertumoral heterogeneity of molecular phenotype and analysis of prognosis in multifocal and multicentric breast cancer].Semantic proximity Read ↗

Breast cancer heterogeneity: Evaluation of clonality in primary and metastatic lesionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.