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Article

Genomic structure of the mouse Ap3b1 gene in normal and pearl mice.

Genomics - 1 Nov 2000

Feng L, Rigatti B W, Novak E K, Gorin M B, Swank R T

Abstract excerpt

The mouse hypopigmentation mutant pearl is an established model for Hermansky-Pudlak syndrome (HPS), a genetically heterogenous disease with misregulation of the biogenesis/function of melanosomes, lysosomes, and platelet dense granules. The pearl (Ap3b1) gene encodes the beta3A subunit of the AP-3 adaptor complex, which regulates vesicular trafficking. The genomic structure of the normal Ap3b1 gene includes 25...

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Share to Adaptor Proteins, Vesicular Transport
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Source

Identifiers

PMID: 11056055
DOI: 10.1006/geno.2000.6350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Genomic structure of the mouse Ap3b1 gene in normal and pearl mice.PMID 11056055Read ↗

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