Article
hOGG1 promoter methylation, hOGG1 genetic variants and their interactions for risk of coal-borne arsenicosis: A case-control study.
Environmental toxicology and pharmacology - 1 Apr 2020
Ma Lu, Liang Bing, Yang Yuan, Chen Liyuan, Liu Qizhan, Zhang Aihua
Abstract excerpt
To identify the effect of hOGG1 methylation, Ser326Cys polymorphism and their interactions on the risk of coal-borne arsenicosis, 113 coal-borne arsenicosis subjects and 55 reference subjects were recruited. Urinary arsenic contents were analyzed with ICP-MS. hOGG1 methylation and Ser326Cys polymorphism was measured by mehtylation-specific PCR and restriction fragment length polymorphism PCR in PBLCs,...
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