Cystic fibrosis transmembrane conductance regulator mediates tenogenic differentiation of tendon‐derived stem cells and tendon repair: accelerating tendon injury healing by intervening in its downstream signaling

Abstract excerpt

ABSTRACT Tendons are a mechanosensitive tissue, which enables them to transmit to bone forces that are derived from muscle. Patients with tendon injuries, such as tendinopathy or tendon rupture, were often observed with matrix degeneration, and the healing of tendon injuries remains a challenge as a result of the limited understanding of tendon biology. Our study demonstrates that the stretch‐mediated activation...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiovascular Effects of Exercise
• Share to Cellular Mechanics and Interactions