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Article

A Single Amino Acid at Position 431 of the PB2 Protein Determines the Virulence of H1N1 Swine Influenza Viruses in Mice.

Journal of virology - 31 Mar 2020

Xu Chengzhi, Xu Bangfeng, Wu Yunpu, Yang Shiman, Jia Yunhui, Liang Wenhua, Yang Dawei, He Likun, Zhu Wenfei, Chen Yan, Yang Huanliang, Yu Benliang, Wang Dayan, Qiao Chuanling

Abstract excerpt

Genetic reassortments occurred continuously among multiple subtypes or genotypes of influenza viruses prevalent in pigs. Of note, some reassortant viruses bearing the internal genes of the 2009 pandemic H1N1 (2009/H1N1) virus sporadically caused human infection, which highlights their potential threats to human public health. In this study, we performed phylogenetic analysis on swine influenza viruses (SIVs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31996432
DOI: 10.1128/JVI.01930-19
PMCID: PMC7108842

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