Article
Hypomethylation of LINE-1 repeat elements and global loss of DNA hydroxymethylation in vapers and smokers
30 Jan 2020
Abstract excerpt
The outbreak of vaping-related severe lung injuries and deaths and the epidemic of teen vaping in the U.S. underscore the urgent need for determining the biological consequences of electronic cigarette (e-cig) use. We have investigated the association between vaping and epigenetic changes by quantifying DNA methylation levels in Long Interspersed Nucleotide Element 1 (LINE-1) and global DNA hydroxymethylation...
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