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Article

Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls.

eLife - 28 Jan 2020

Sanor Lucas D, Flowers Grant Parker, Crews Craig M

Abstract excerpt

Axolotls and other salamanders can regenerate entire limbs after amputation as adults, and much recent effort has sought to identify the molecular programs controlling this process. While targeted mutagenesis approaches like CRISPR/Cas9 now permit gene-level investigation of these mechanisms, genetic screening in the axolotl requires an extensive commitment of time and space. Previously, we quantified...

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Identifiers

PMID: 31989926
DOI: 10.7554/eLife.48511
PMCID: PMC6986871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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