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Article

Optimal Virulence, Diffusion and Tradeoffs.

Bulletin of mathematical biology - 22 Jan 2020

Silva Esdras Jafet Aristides da, Castilho César

Abstract excerpt

In this work we propose a variant of a classical SIR epidemiological model where pathogens are characterized by a (phenotypic) mutant trait x. Imposing that the trait x mutates according to a random walk process and that it directly influences the epidemiological components of the pathogen, we studied its evolutionary development by interpreting the tenet of maximizing the basic reproductive number of the...

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PMID: 31970536
DOI: 10.1007/s11538-019-00688-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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