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MiRNA-Related Polymorphisms in miR-146a and TCF21 Are Associated with Increased Susceptibility to Coronary Artery Disease in an Iranian Population.

Genetic testing and molecular biomarkers - 1 May 2016

Bastami Milad, Ghaderian Sayyed Mohamad Hossein, Omrani Mir Davood, Mirfakhraie Reza, Vakili Hossein, Parsa Saeed Alipour, Nariman-Saleh-Fam Ziba, Masotti Andrea

Abstract excerpt

AIMS: Recent studies have suggested that single-nucleotide polymorphisms (SNPs) in miRNA genes or their binding sites may alter an individual's susceptibility to coronary artery disease (CAD). In the present study, the association between two such SNPs (rs2910164 in miR-146a and rs12190287, which disrupts miRNA binding to TCF21) and CAD, in an Iranian population, was evaluated and in silico analyses were...

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Identifiers

PMID: 26909569
DOI: 10.1089/gtmb.2015.0253

Genes

CAD
TCF21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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