Article
Detection in two hospitals of transferable ceftazidime-avibactam resistance in Klebsiella pneumoniae due to a novel VEB β-lactamase variant with a Lys234Arg substitution, Greece, 2019.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 1 Jan 2020
Voulgari E, Kotsakis S D, Giannopoulou P, Perivolioti E, Tzouvelekis L S, Miriagou V
Abstract excerpt
Two ceftazidime-avibactam (CAZ-AVI)-resistant Klebsiella pneumoniae carbapenemase (KPC)-positive K. pneumoniae strains, including one pandrug resistant, were isolated in 2019 from two Greek hospitals. The strains were sequence types (ST)s 258 and 147 and both harboured similar self-transmissible IncA/C2 plasmids encoding a novel Lys234Arg variant of the Vietnamese extended-spectrum β-lactamase (VEB)-1, not...
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