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Ceftazidime-avibactam resistance in Klebsiella pneumoniae: A growing public health concern across diverse sublineages, 2019–2024

1 Jul 2025

Abstract excerpt

OBJECTIVES: Strains resistant to last-line β-lactam antibiotics pose a global public health threat, requiring close monitoring and action. This study investigated ceftazidime-avibactam (CAZ-AVI) resistance rates among Klebsiella pneumoniae infection isolates from northern Portugal in a 6-year period. METHODS: A total of 539 carbapenem-resistant or KPC-positive K. pneumoniae isolates identified between May 2019...

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PMID: 40582405
DOI: 10.1016/j.jgar.2025.06.016

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