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Article

Transcriptional analysis of THP-1 cells infected with Leishmania infantum indicates no activation of the inflammasome platform

21 Jan 2020

Abstract excerpt

Leishmaniasis is caused by intracellular parasites transmitted to vertebrates by sandfly bites. Clinical manifestations include cutaneous, mucosal or visceral involvement depending upon the host immune response and the parasite species. To assure their survival inside macrophages, these parasites developed a plethora of highly successful strategies to manipulate various immune system pathways. Considering that...

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PMID: 31961876
DOI: 10.1371/journal.pntd.0007949

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