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Exosomal miRNA-let-7i-5p from bone marrow mesenchymal stem cells protects against myocardial infarction by inhibiting myocardial apoptosis

1 Jan 2024

Abstract excerpt

OBJECTIVES: To elucidate the regulatory effect of exosomes secreted by bone marrow mesenchymal stem cells (BMSCs-exosomes) on cardiomyocyte apoptosis through miRNA-let-7i-5p in myocardial infarction. METHODS: BMSCs-exosomes were extracted, and their morphology and size distribution were analyzed using transmission electron microscope. Expression of exosome surface markers was determined by western blot. H9C2...

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PMID: 39678588
DOI: 10.62347/vxnd1945

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