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Evaluation of swine enteroids as in vitro models for Lawsonia intracellularis infection1,2

16 Jan 2020

Abstract excerpt

The enteric pathogen Lawsonia intracellularis is one of the main causes of diarrhea and compromised weight gain in pigs worldwide. Traditional cell-line cultures have been used to study L. intracellularis pathogenesis. However, these systems fail to reproduce the epithelial changes observed in the intestines of L. intracellularis-infected pigs, specifically, the changes in intestinal cell constitution and gene...

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PMID: 31943029
DOI: 10.1093/jas/skaa011

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