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Toward the realization of cardiac regenerative medicine using pluripotent stem cells

13 Jan 2020

Abstract excerpt

Heart transplantation (HT) is the only radical treatment available for patients with end-stage heart failure that is refractory to optimal medical treatment and device therapies. However, HT as a therapeutic option is limited by marked donor shortage. To overcome this difficulty, regenerative medicine using human-induced pluripotent stem cells (hiPSCs) has drawn increasing attention as an alternative to HT....

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PMID: 31938077
DOI: 10.1186/s41232-019-0110-4

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