Article
Molecular Characterization of Muellerian Tumors of the Urinary Tract.
Genes - 7 Jun 2021
Ortiz-Brüchle Nadina, Wucherpfennig Sophie, Rose Michael, Garczyk Stefan, Bertz Simone, Hartmann Arndt, Reis Henning, Szarvas Tibor, Kiss András, Bremmer Felix, Golz Reinhard, Knüchel Ruth, Gaisa Nadine T
Abstract excerpt
In the 2016 WHO classification of genitourinary tumors Muellerian tumors of the urinary tract (MTUT) comprise clear cell adenocarcinomas and endometrioid carcinomas. Since these rare tumors remained understudied, we aimed to characterize their molecular background by performing DNA- and RNA-based targeted panel sequencing. All tumors (n = 11) presented single nucleotide alterations (SNVs), with ARID1A mutations...
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