Article
Afatinib for the Treatment of NSCLC Harboring Uncommon EGFR Mutations: A Database of 693 Cases.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 May 2020
Yang James Chih-Hsin, Schuler Martin, Popat Sanjay, Miura Satoru, Heeke Simon, Park Keunchil, Märten Angela, Kim Edward S
Abstract excerpt
INTRODUCTION: Limited clinical data are available regarding the efficacy of EGFR tyrosine kinase inhibitors (EGFR TKIs) in patients with NSCLC harboring uncommon EGFR mutations. This pooled analysis assessed the activity of afatinib in 693 patients with tumors harboring uncommon EGFR mutations treated in randomized clinical trials, compassionate-use and expanded-access programs, phase IIIb trials,...
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