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Article

Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic cancer - 1 Nov 2021

Li Teng, Wang Shouzheng, Ying Jianming, Wang Yan, Hu Xingsheng, Hao Xuezhi, Xu Ziyi, Xing Puyuan, Li Junling

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have improved the prognosis of mutant lung cancer; however, the clinical application value of TKIs for nonclassical EGFR mutation is unclear, especially for patients with rare uncommon mutations. METHODS: A retrospective study based on electronic medical records was conducted to collect data on the effectiveness of afatinib in...

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Identifiers

PMID: 34549528
DOI: 10.1111/1759-7714.14156
PMCID: PMC8563151

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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