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Article

KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies.

Clinical epigenetics - 10 Jan 2020

Lavery William J, Barski Artem, Wiley Susan, Schorry Elizabeth K, Lindsley Andrew W

Abstract excerpt

The type 2 lysine methyltransferases KMT2C and KMT2D are large, enzymatically active scaffold proteins that form the core of nuclear regulatory structures known as KMT2C/D COMPASS complexes (complex of proteins associating with Set1). These evolutionarily conserved proteins regulate DNA promoter and enhancer elements, modulating the activity of diverse cell types critical for embryonic morphogenesis, central...

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Identifiers

PMID: 31924266
DOI: 10.1186/s13148-019-0802-2
PMCID: PMC6954584

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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